Pharmaceutical Profiling in Drug Discovery for Lead Selection

Publication Date: 2005-12-05

Edited by Ronald T. Borchardt, Edward H. Kerns, Christopher A. Lipinski, Dhiren R. Thakker, and Binghe Wang

Volume 1 of the AAPS Press series, Biotechnology: Pharmaceutical Aspects. Based on a 2003 AAPS workshop of the same name, Pharmaceutical Profiling in Drug Discovery for Lead Selection emphasizes the importance of accuracy in the prediction, measurement, and application of physiochemical and ADME properties, not only to guarantee successful lead selection in "hit-to-lead" research but also to avoid the common pitfalls that arise when property information is lacking. Its contributors include highly experienced leaders from both industry and academia, with specialization in advanced methods for in silico, physiochemical, permeability, in vitro, and ADME, as well as in medicinal chemistry applications on pharmaceutical property information.

ISBN: 978-0-9711767-9-9

Supporting Information and Data 

Table of Contents  

Question & Answer/Panel Discussion Transcripts  

Session I: In Silico Tools 

Session II: Physicochemical Methods  

Session III: Permeability 

Session IV: ADME 

Session V: Application of Property Information to Lead Selection
Suggested List Price:
$164.25 (AAPS member)
$219.00 (nonmember)

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